Differential Expression

Cancer Selection:

Threshold:
  
   
User Guide:

Retrieve the list of genes RNA expression levels are most differentially expressed between normal and cancer samples.
  • Cancer selection: Select cancer type of interest from the drop-down menu.
  • Threshold: Settings used to filter gene list.
    • FDR Adjusted p-value: Set custom FDR (False Discovery Rate) adjusted p-value (q-value). Return genes with a q-value equal to or lower than threshold.
    • |log2FC|: Set the log2 transformed fold change threshold. (upregulated/downregulated)

*Direct comparison of tumor and normal tissues may identify not only differences related to tumorigenesis, but also differences in tissue composition. Thus, the comparison results should be interpreted with caution.